ISO 7835:2026

International
Standard
ISO 7835
First edition
Traditional Chinese medicine —
2026-08
Schisandra chinensis fruit
Reference number
© ISO 2026
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ii
Contents Page
Foreword .iv
Introduction .v
1 Scope . 1
2 Normative references . 1
3 Terms and definitions . 1
4 Description . . 2
5 Requirements and recommendations . 2
5.1 General characteristics .2
5.2 Macroscopic characteristics .2
5.3 Microscopic characteristics .3
5.4 Moisture .3
5.5 Total ash .4
5.6 Identification of Schisandra chinensis fruit .4
5.7 Differentiation of Schisandra chinensis fruit from Schisandra sphenanthera fruit .4
5.8 Content of marker compounds .4
5.9 Heavy metals .4
5.10 Pesticide residues .4
5.11 Sulfur dioxide . .4
6 Sampling . 4
7 Test methods . 5
7.1 Macroscopic identification .5
7.2 Microscopic identification .5
7.3 Determination of moisture content .5
7.4 Determination of total ash content .5
7.5 Identification of schisandrin, gomisin A and gomisin N .5
7.6 Determination of schisandrin, gomisin A and gomisin N content .5
7.7 Determination of heavy metals .5
7.8 Determination of pesticide residues .5
7.9 Determination of sulfur dioxide .5
8 Test report . 5
9 Packaging, storage and transportation . 6
10 Marking and labelling . 6
Annex A (informative) Identification of schisandrin, gomisin A and gomisin N . 7
Annex B (Informative) Determination of schisandrin, gomisin A and gomisin N content . 9
Annex C (informative) Differentiation of Schisandra chinensis fruit from Schisandra sphenathera
fruit .12
Annex D (informative) Reference information for national and regional requirements .15
Bibliography .16

iii
Foreword
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Traditional Chinese medicine.
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iv
Introduction
Schisandra chinensis fruit is a well-known traditional herbal medicine for thousands of years. Schisandra
chinensis fruit has been used for the treatment of chronic cough and asthma, diabetes, and urinary tract
disorders. Pharmacological studies have revealed that Schisandra chinensis fruit possesses various biological
activities, including hepatoprotective, anti-inflammatory, antioxidant and antitumor activities.
Schisandra chinensis fruit has been officially documented as a traditional herbal medicine in the
[2] [3]
pharmacopoeias of several countries, including China (named wu wei zi), Japan (named gomishi), and
[1]
Korea (named omija), as a traditional herbal medicine. Recently, the monograph of Schisandra chinensis
fruit has also been included in the European pharmacopoeia and the United States Pharmacopoeia, where it
is regulated as a dietary supplement.
The active medicinal constituents of Schisandra chinensis fruit contribute to its high market demand and
utilization. Given the extensive cultivation and widespread use of this botanical, products in the herbal
market are frequently adulterated with Schisandra sphenanthera fruit. This substitution occurs due to the
morphological similarity between the two species and the lower cost of Schisandra sphenanthera fruit.
Although the two Schisandra species differ significantly in their chemical profiles and biological activities,
they are both commonly referred to as “Schisandra fruit” in commercial trade, leading to inconsistent
quality in industrial applications.
Therefore, the establishment of an international standard for Schisandra chinensis fruit is necessary to
support the clinical effectiveness, safety and quality consistency of this valuable traditional herbal medicine
in international trade.
As national implementation can differ, national standards bodies are invited to modify the values given in
5.5 in their national standards. Examples of national and regional values are given in Annex D.

v
International Standard ISO 7835:2026(en)
Traditional Chinese medicine — Schisandra chinensis fruit
1 Scope
This document specifies the minimum requirements and test methods for Schisandra chinensis fruit which is
derived from Schisandra chinensis (Turcz.) Baill.
It is applicable to Schisandra chinensis fruit that is sold and used as a medicinal material in international
trade, including Chinese materia medica.
2 Normative references
The following documents are referred to in the text in such a way that some or all of their content constitutes
requirements of this document. For dated references, only the edition cited applies. For undated references,
the latest edition of the referenced document (including any amendments) applies.
ISO 18664, Traditional Chinese Medicine — Determination of heavy metals in herbal medicines used in
Traditional Chinese Medicine
ISO 21310, Traditional Chinese medicine — Microscopic examination of medicinal herbs
ISO 21371, Traditional Chinese medicine — Labelling requirements of products intended for oral or topical use
ISO 22217, Traditional Chinese medicine —Storage requirements for raw materials and decoction pieces
ISO 22258, Traditional Chinese medicine — Determination of pesticide residues in natural products by gas
chromatography
ISO 22590, Traditional Chinese medicine — Determination of sulfur dioxide in natural products by titration
ISO 23723:2021, Traditional Chinese medicine — General requirements for herbal raw material and materia
medica
3 Terms and definitions
For the purposes of this document, the following terms and definitions apply.
ISO and IEC maintain terminology databases for use in standardization at the following addresses:
— IEC Electropedia: available at https:// www .iso .org/ obp
— ISO Online browsing platform: available at https:// www .electropedia .org/
3.1
Schisandra chinensis fruit
dried and ripe fruit from Schisandra chinensis (Turcz.) Baill. (Fam. Magnoliaceae).
3.2
Schisandra sphenanthera fruit
dried and ripe fruit from Schisandra sphenanthera Rehd. et Wils. (Fam. Magnoliaceae).

3.3
final sample
sample for the test required in this document
[SOURCE: ISO 23193:2020, 3.4]
4 Description
Schisandra chinensis fruit is shown in Figure 1.
Key
A fruiting branch of Schisandra chinensis (Turcz.) Baill.
B fruits of Schisandra chinensis (Turcz.) Baill.
1 fruit
2 seed
3 peduncle
Figure 1 — Structure of the plant of Schisandra chinensis fruit
5 Requirements and recommendations
5.1 General characteristics
The following requirements shall be met before sampling.
a) Schisandra chinensis fruit shall be clean and free from foreign matter.
b) The presence of living insects, moulds and external contaminants which are visible to the naked eye
shall not be permitted.
5.2 Macroscopic characteristics
a) The dried fruit is of an irregular and flat globular shape. The diameter of the dried fruit containing one
...